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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM4 All Species: 0
Human Site: S105 Identified Species: 0
UniProt: P33991 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33991 NP_005905.2 863 96558 S105 R V E G T P R S G V R G T P V
Chimpanzee Pan troglodytes XP_528129 863 96543
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535063 929 104136
Cat Felis silvestris
Mouse Mus musculus P49717 862 96718
Rat Rattus norvegicus NP_387500 862 96552
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515513 863 97108
Chicken Gallus gallus XP_424376 859 96866
Frog Xenopus laevis P30664 863 97105
Zebra Danio Brachydanio rerio NP_944595 750 84021
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q26454 866 96592
Honey Bee Apis mellifera XP_624670 636 71159
Nematode Worm Caenorhab. elegans Q21902 759 84917
Sea Urchin Strong. purpuratus XP_801985 910 101460
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43299 716 80315
Baker's Yeast Sacchar. cerevisiae P30665 933 104985
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 87.6 N.A. 94.9 95.1 N.A. 92.4 86.3 85.7 71.3 N.A. 60.1 42.1 28.1 63.3
Protein Similarity: 100 100 N.A. 90 N.A. 97 97.3 N.A. 96.1 93.1 92.9 78.7 N.A. 77.3 54.3 46.9 76.3
P-Site Identity: 100 0 N.A. 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 0 0 0
P-Site Similarity: 100 0 N.A. 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 0 0 0
Percent
Protein Identity: N.A. N.A. N.A. 28.9 42.6 N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 62.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 100 0 0 0 0 100 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 100 0 0 0 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 100 0 0 0 0 0 100 0 0 0 100 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 100 0 0 0 0 0 0 0 100 0 0 % T
% Val: 0 100 0 0 0 0 0 0 0 100 0 0 0 0 100 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _